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23andme Raw Data File Lookup

Created By
obuchowski10 months ago
Querying genotype data by RSID from 23andMe raw file
Overview

What is 23andMe Raw Data MCP Server?

23andMe Raw Data MCP Server is a Model Context Protocol server that enables LLMs to query 23andMe raw genotype files by RSID (Reference SNP cluster ID). It parses TSV-formatted 23andMe raw data files and provides instant access to genetic information, making it easy to look up specific genetic variants and their associated genotypes.

How to use 23andMe Raw Data MCP Server?

To use 23andMe Raw Data MCP Server, install it via npm and run it with your 23andMe raw data file as an argument. Configure it in your Claude settings by specifying the path to the server and your data file. The server provides a tool called get_genotype_by_rsid that allows you to query specific genetic variants by their RSID and retrieve the corresponding genotype.

Key features of 23andMe Raw Data MCP Server?

  • Fast genotype lookup by RSID from 23andMe raw data files
  • Handles standard TSV-formatted 23andMe raw data with header comments
  • Returns "--" for missing or invalid RSIDs for consistent error handling
  • Lightweight Node.js implementation with minimal dependencies
  • Easy integration with Claude and other MCP-compatible clients
  • Supports all standard RSID formats (e.g., rs1234567)

Use cases of 23andMe Raw Data MCP Server?

  • Researching specific genetic variants and their personal genotypes
  • Educational exploration of genomic data and SNPs
  • Building genetic analysis workflows with LLM assistance
  • Cross-referencing research findings with personal genetic data
  • Automating genetic data queries in research applications

FAQ from 23andMe Raw Data MCP Server?

Can 23andMe Raw Data MCP Server handle all RSID formats? Yes, the server supports standard RSID formats that match the pattern of letters followed by numbers (e.g., rs1234567).

Is the genetic data secure? Yes, all data processing happens locally on your machine. The server only reads your data file and doesn't transmit genetic information externally.

What happens if an RSID isn't found in my data? The server returns "--" for any missing or invalid RSIDs, which is consistent with how 23andMe represents missing data.

Is 23andMe Raw Data MCP Server free to use? Yes, the server is open-source and free to use under the MIT License.

Server Config

{
  "mcpServers": {
    "23andMe Genotype Lookup": {
      "command": "node",
      "args": [
        "~/src/index.js",
        "~/sample-data.txt"
      ]
    }
  }
}
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