Unofficial Ensembl MCP Server

What is Ensembl MCP Server?

The Ensembl MCP Server is an unofficial Model Context Protocol server that provides access to the Ensembl REST API for genomic data, comparative genomics, and biological annotations.

How to use Ensembl MCP Server?

To use the Ensembl MCP Server, clone the repository, install dependencies, build the server, and configure it with Claude Desktop to access genomic data through natural language queries.

Key features of Ensembl MCP Server?

• Gene and transcript information retrieval
• Genomic sequence extraction and translation
• Comparative genomics tools for homolog detection and phylogenetic analysis
• Variant data retrieval and consequence prediction
• Access to regulatory features and annotations
• Batch processing capabilities for multiple queries

Use cases of Ensembl MCP Server?

1. Researchers can look up gene information and sequences for their studies.
2. Bioinformaticians can analyze genetic variants and their effects.
3. Educators can use the server to demonstrate genomic concepts in teaching.

FAQ from Ensembl MCP Server?

• What types of data can I access?

You can access genomic sequences, gene annotations, variant data, and regulatory features across multiple species.

• Is there a limit on API requests?

Yes, the server respects Ensembl's rate limiting guidelines, allowing a maximum of 15 requests per second.

• Can I contribute to the project?

Yes! Contributions are welcome, and you can help improve the server by ensuring TypeScript compliance and updating documentation.