Cortellis MCP Server

MCP Server for searching drugs and exploring ontology terms in the Cortellis database.

Installation

# Using npm
npm install @uh-joan/cortellis-mcp-server

Quick Start

1. Set up your environment variables:

CORTELLIS_USERNAME=your_username
CORTELLIS_PASSWORD=your_password
USE_HTTP=true  # Optional: run as HTTP server
PORT=3000      # Optional: specify port for HTTP server

2. Run the server:

# As MCP server
npx cortellis-mcp-server

# As HTTP server
USE_HTTP=true PORT=3000 npx cortellis-mcp-server

Tools

1. search_drugs

   • Search for drugs in the Cortellis database
   • Optional Inputs:
     • query (string) - Raw search query
     • company (string) - Company ID for the developing company (e.g., "18614")
     • indication (string) - Indication ID (numeric ID only, e.g., "238" for Obesity). Use explore_ontology to find the correct ID.
     • action (string) - Target specific action (e.g., glucagon)
     • phase (string) - Development status:
       • Uses LINKED format with short codes: S, DR, CU, C1-C3, PR, R, L, OL, NDR, DX, W
       • Supports OR/AND operators: "L OR C3"
       • Examples:
         • phase: "L"
         • phase: "C3 OR PR"
       • Status codes:
         • S: Suspended
         • DR: Discovery/Preclinical
         • CU: Clinical (unknown phase)
         • C1-C3: Phase 1-3 Clinical
         • PR: Pre-registration
         • R: Registered
         • L: Launched
         • OL: Outlicensed
         • NDR: No Development Reported
         • DX: Discontinued
         • W: Withdrawn
     • phase_terminated (string) - Last phase before NDR/DX
       • Uses short format with double colon: S, DR, CU, C1-C3, PR, R, L, OL, NDR, DX, W
       • Examples:
         • phase_terminated: "C2"
         • phase_terminated: "C2 OR C3"
     • technology (string) - Drug technology (e.g., small molecule)
     • drug_name (string) - Name of the drug
     • country (string) - Country ID (e.g., "US")
     • offset (number) - For pagination
   • Returns: JSON response with drug information and development status

2. explore_ontology

   • Explore taxonomy terms in the Cortellis database
   • Optional Inputs (at least one required):
     • term (string) - Generic search term
     • category (string) - Category to search within
     • action (string) - Target specific action
     • indication (string) - Disease/condition
     • company (string) - Company name
     • drug_name (string) - Drug name
     • target (string) - Drug target
     • technology (string) - Drug technology
   • Returns: JSON response with matching taxonomy terms

3. get_drug

   • Return the entire drug record with all available fields for a given identifier
   • Required Input:
     • id (string) - Numeric Drug Identifier (e.g. "101964" for tirzepatide, not the drug name)
   • Example: { "tool-name": "get_drug", "Tool_Parameters": { "id": "101964" } }
   • Returns: JSON response with complete drug record

4. get_drug_swot

   • Return SWOT analysis complementing chosen drug record
   • Required Input:
     • id (string) - Numeric Drug Identifier (e.g. "101964" for tirzepatide, not the drug name)
   • Example: { "tool-name": "get_drug_swot", "Tool_Parameters": { "id": "101964" } }
   • Returns: JSON response with SWOT analysis for the drug

5. get_drug_financial

   • Return financial commentary and data (actual sales and consensus forecast)
   • Required Input:
     • id (string) - Numeric Drug Identifier (e.g. "101964" for tirzepatide, not the drug name)
   • Example: { "tool-name": "get_drug_financial", "Tool_Parameters": { "id": "101964" } }
   • Returns: JSON response with financial data and commentary

6. get_company

   • Return the entire company record with all available fields for a given identifier
   • Required Input:
     • id (string) - Numeric Company Identifier (not the company name)
   • Example: { "tool-name": "get_company", "Tool_Parameters": { "id": "12345" } }
   • Returns: JSON response with complete company record

7. search_companies

   • Search for companies in the Cortellis database
   • Optional Inputs:
     • query (string) - Raw search query
     • company_name (string) - Company name to search for
     • hq_country (string) - Company headquarters country
     • deals_count (string) - Count for all distinct deals where company is principal/partner
       • Format: '<20' for less than 20 deals
       • Format: '20' or '>20' for greater than 20 deals (default behavior)
     • indications (string) - Top 10 indication terms
     • actions (string) - Top 10 target-based action terms
     • technologies (string) - Top 10 technologies terms
     • company_size (string) - The size of a company based on market capitalization in billions USD
       • Format: '<2' for less than $2B
       • Format: '2' or '>2' for greater than $2B (default behavior)
     • status (string) - Highest status of linked drugs
     • offset (number) - For pagination
   • Returns: JSON response with company information

Features

• Direct access to Cortellis drug database
• Comprehensive drug development status search
• Ontology/taxonomy term exploration
• Detailed drug information retrieval
• SWOT analysis for drugs
• Financial data and forecasts
• Structured JSON responses
• Pagination support for large result sets

HTTP API Endpoints

When running in HTTP mode (USE_HTTP=true), the following REST endpoints are available:

1. POST /search_drugs

   • Search for drugs with optional filters
   • Body: JSON object with search parameters (see search_drugs tool inputs)

2. POST /explore_ontology

   • Search taxonomy terms
   • Body: JSON object with search parameters (see explore_ontology tool inputs)

3. GET /drug/:id

   • Get complete drug record by ID
   • Parameters:
     • id: Drug identifier

4. GET /drug/:id/swot

   • Get SWOT analysis for a drug
   • Parameters:
     • id: Drug identifier

5. GET /drug/:id/financial

   • Get financial data and forecasts for a drug
   • Parameters:
     • id: Drug identifier

6. GET /company/:id

   • Get complete company record by ID
   • Parameters:
     • id: Company identifier

7. POST /search_companies

   • Search for companies with optional filters
   • Body: JSON object with search parameters (see search_companies tool inputs)

Setup

Environment Variables

The server requires Cortellis API credentials:

CORTELLIS_USERNAME=your_username
CORTELLIS_PASSWORD=your_password

Installing on Claude Desktop

Before starting make sure Node.js is installed on your desktop for npx to work.

1. Go to: Settings > Developer > Edit Config

2. Add the following to your claude_desktop_config.json:

{
  "mcpServers": {
    "cortellis": {
      "command": "npx",
      "args": [
        "-y",
        "@uh-joan/cortellis-mcp-server"
      ],
      "env": {
        "CORTELLIS_USERNAME": "your_username",
        "CORTELLIS_PASSWORD": "your_password"
      }
    }
  }
}

3. Restart Claude Desktop and start exploring drug development data!

Build (for devs)

git clone https://github.com/uh-joan/cortellis-mcp-server.git
cd cortellis-mcp-server
npm install
npm run build

For local development:

# Copy example environment file
cp .env.example .env

# Edit .env with your credentials
vim .env  # or use your preferred editor

# Start the server
npm run start

Docker

docker build -t cortellis-mcp-server .
docker run -i --env-file .env cortellis-mcp-server

License

This MCP server is licensed under the MIT License.

Disclaimer

Cortellis™ is a commercial product and trademark of Clarivate Analytics. This MCP server requires valid Cortellis API credentials to function. To obtain credentials and learn more about Cortellis, please visit Clarivate's Cortellis page.

This project is not affiliated with, endorsed by, or sponsored by Clarivate Analytics. All product names, logos, and brands are property of their respective owners.

Contributing

Contributions are welcome! Please feel free to submit a Pull Request. For major changes, please open an issue first to discuss what you would like to change.

Versioning

We use SemVer for versioning. For the versions available, see the tags on this repository.